UV absorbance spectroscopy is traditionally considered inapplicable to the measurement of the dissolution of products with multiple APIs or matrix interference with a non-active component. This is due to the technique’s non-selective nature. Because of this, these samples are commonly analyzed using a separation technique such as HPLC or UPLC, despite the extra cost and time. This webinar discusses the use of Classical Least Squares (CLS) and Fiber Optic UV to enable measurements of these samples using UV detection.
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